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Beilstein J. Org. Chem. 2012, 8, 1233–1240, doi:10.3762/bjoc.8.138
Graphical Abstract
Figure 1: Biologically interesting α-fluorinated β-ketoesters.
Scheme 1: Preparation of quinine ester C-1.
Figure 2: Promoters for asymmetric fluorination.
Scheme 2: Preparation of 2a by using recycled quinine ester C-1.
Figure 3: The asymmetric fluorination of various β-ketoesters.